Coming soon from EpitomeRx: Nº 29 copper peptide cream. Learn more
Prepared to order

Wrinkles and Aging Skin

Prescription face creams for aging skin, most made in our GHK-Cu peptide cream base.

  • Cream
PricingQuoted when we call to confirm your order
Get started Prescribers: order forms (portal)

Prescribers: e-prescribe this prescription · Licensed to fill prescriptions for patients in California

  • Estriol 0.3% cream with a 91-day use-by date
  • Tretinoin, estriol and peptide formulas
  • Strengths set by your prescriber
  • Prepared for one patient

Compounded medications are made for one patient from a prescriber's order. They are not FDA approved. This page is for general information, not medical advice.

About skin changes with age

Skin changes with age, sun exposure and hormones. After menopause, lower estrogen levels are linked to thinner, drier skin. Your prescriber looks at your skin, health history and goals before choosing a cream.

We compound only when there is a clinical reason a commercially available product won't work for you, such as a strength or combination that isn't made commercially, a different base because of an allergy or sensitivity, or a different form.

Formulas we commonly prepare

Your prescriber chooses the formula and strength.

Featured

  • Estriol 0.3% in GHK-Cu Peptide Cream Base (use within 91 days when made to the tested formula and packaged in an airless pump)

Cream, 30 g

  • Tretinoin 0.05% / Hyaluronic Acid Cream

In GHK-Cu Peptide Cream Base (15 g or 30 g)

  • Tretinoin 0.1%
  • Tretinoin 0.02% with sodium hyaluronate and aloe vera
  • Nifedipine 0.5% / Estriol 0.3% / Tretinoin 0.025%
  • Estriol 0.3% with palmitoyl pentapeptide
  • Estriol 0.3% / Methylene Blue with DMAE
  • Estriol 0.3% / Tretinoin 0.025% / Methylene Blue with palmitoyl pentapeptide
  • Progesterone 2% with DMAE and sodium hyaluronate
  • Alpha Lipoic Acid 3% with palmitoyl pentapeptide, vitamins E and A, and dexpanthenol

Don't see what your prescriber wrote? Call us at 626.631.6150.

How to use

Follow the directions on your label. Face creams are usually applied as a thin layer, or a pea-sized amount for tretinoin, once or twice a day. Wash your hands after applying.

Before you start

Estriol and progesterone are hormones. Tell your prescriber if you are pregnant, planning a pregnancy, breastfeeding, or have had a hormone-sensitive cancer or blood clots.

Tretinoin increases sun sensitivity and can cause dryness, peeling or irritation, especially at first. It is not for use during pregnancy.

Estrogen can make some people more likely to develop dark patches (melasma). Daily sunscreen helps.

Stop and call your prescriber if you have severe redness, burning, swelling or a rash.

Step 1

Send your prescription

Your prescriber e-prescribes to EpitomeRx, faxes the prescription to 626.631.6151, or calls it in. Already have a prescription elsewhere? We can transfer it.

Step 2

We review and call you

A pharmacist checks the prescription for accuracy and formulation needs, then we call you to confirm details, pricing, timing and delivery. Payment is collected before we compound.

Step 3

We compound it

Your medication is prepared in our Arcadia laboratory to your provider's exact instructions and checked before it is dispensed.

Step 4

Delivered to your door

We ship anywhere in California. Local pickup in Arcadia is available by calling ahead.

For prescribers

Order on the dermatology order forms (in the prescriber portal), by e-prescription, fax or phone. Tretinoin and progesterone are NIOSH hazardous drugs and are compounded under USP <800>. For items with a similar commercially available active, include the reason for compounding. Call 626.631.6150 for other strengths or formulas.

Common questions

Do I need a prescription?

Yes. Your prescriber writes the prescription. We do not prescribe.

What is GHK-Cu Peptide Cream Base?

It is a cream base that contains the copper peptide GHK-Cu along with other peptides, and it is made without fragrance or dyes. We add the prescription ingredients your prescriber writes to it.

Why is estriol featured?

Estriol 0.3% in this base has been tested by PCCA for stability, so when we make it exactly to that formula and package it in an airless pump it can be used for 91 days instead of 35.

How long is it good for?

Use it by the date on your label: 35 days for most formulas, 91 days for the featured estriol cream.

Can I use it with my other skincare?

Usually, yes, but don't apply it at the same time as acids, benzoyl peroxide, hydroquinone or kojic acid. Use them at different times of day, or ask our pharmacist.

Do I need sunscreen?

Yes. Tretinoin can make your skin more sensitive to the sun, and estrogen can make some people more likely to develop dark patches (melasma). Use sunscreen every day.

Can I use these if I'm pregnant or breastfeeding?

Several of these ingredients are not for use in pregnancy. Tell your prescriber if you are pregnant, planning a pregnancy or breastfeeding.

Are compounded medications FDA approved?

No. Compounded medications are prepared by a pharmacy for one patient from a prescription, and FDA has not reviewed their safety, effectiveness or quality. We prepare them following USP standards for nonsterile and hazardous drug compounding.

How does my prescriber send the prescription?

By e-prescription, fax or phone. See how to e-prescribe.

Do you ship?

We ship within California only. Free standard shipping on orders of $99 and up; $10 under $99. Local pickup at our Arcadia pharmacy is by appointment.

Licensed service area

Serving patients across California

EpitomeRx is licensed by the California State Board of Pharmacy. We ship anywhere in California. Local pickup in Arcadia is available by calling ahead.

Serving Arcadia, Pasadena, Monrovia, San Marino, Temple City, the San Gabriel Valley and all of California.

Shipping times and pickup details

Arcadia
Licensed service areaOur pharmacy